Research position: urine-derived liquid biopsy in pediatric cancer

Barneklinikken, Oslo universitetssykehus HF

A 2-year 100% scientist position with possibility of elongation for a highly motivated and skilled researcher is available at the Department of Pediatric Research, OUS Rikshospitalet ( on a project funded by the Norwegian Cancer Society.

Liquid biopsies leverage circulating molecular structures from body fluids, facilitating a less invasive yet more comprehensive diagnostic approach. Especially for childhood cancer patients it is crucial to obtain temporal and spatial insights that capture the tumor's heterogeneity and evolving structure over time. Peripheral blood is the common source for liquid biopsies; however, in childhood cancer patients, the sample volume is often restricted. In contrast, urine-derived samples are both abundant and harmless. Furthermore, recent technological advances allow for genomic, transcriptomic, proteomic, metabolomic, and methylation profiling using urine. Circulating cell‑free DNA (cfDNA),...