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Research Associate in Structural and Mechanistic Enzymology of Bacteriophage

University of York · York, England, United Kingdom

Location
York
Job Type
Full-time
Posted
July 16, 2026

Job Description

Role

To conduct research under the supervision of senior colleagues and to contribute to the production of research, in particular to:

  • Engineer enzymes to confer novel functionalities

  • Assay enzyme activity using LC-MS/HPLC and biochemical assays

  • Determine the chemical mechanisms underlying enzyme activity

  • Determine enzyme structures using X-ray crystallography

  • Analyse biological samples using TEM and SEM

    • Skills, Experience & Qualification needed

  • Undergraduate degree in Chemistry

  • PhD in enzyme engineering, structural biology, biocatalysis and equivalent experience

  • Knowledge of protein-ligand complex structure determination by X-ray crystallography

  • Knowledge in enzyme engineering including mutant library construction

  • Knowledge in enzyme assaying by LC-MS and HPLC

  • Skills in generating structure- and AI-guided mutant librar...

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